Article
Lack of an association between peroxisome proliferator-activated receptor-gamma gene Pro12Ala polymorphism and adiponectin levels in the polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism - 1 Oct 2004
Orio Francesco, Palomba Stefano, Cascella Teresa, Di Biase Sebastiano, Labella Donato, Russo Tiziana, Savastano Silvia, Zullo Fulvio, Colao Annamaria, Vettor Roberto, Lombardi Gaetano
Abstract excerpt
Polycystic ovary syndrome (PCOS) is one of the most common endocrine metabolic diseases and is characterized by obesity in approximately 50% of those affected. Adiponectin is an adipocyte-derived protein that possesses an antiatherosclerotic action and improves insulin sensitivity. Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) regulates the transcription of several adipocyte-specific genes. The...
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