Article
Polymorphism in the peroxisome proliferator-activated receptor-gamma gene in women with polycystic ovary syndrome.
Human reproduction (Oxford, England) - 1 Mar 2003
Korhonen S, Heinonen S, Hiltunen M, Helisalmi S, Hippeläinen M, Koivunen R, Tapanainen J S, Laakso M
Abstract excerpt
BACKGROUND: In view of the strong evidence implicating peroxisome proliferator-activated receptor-gamma (PPARgamma) in adiposity and insulin resistance a study was carried out to investigate PPARgamma genotype frequencies in women with polycystic ovary syndrome (PCOS) and to elucidate its role in the pathogenesis of the syndrome. METHODS: The study involved 135 women with PCOS and 115 healthy control women who...
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