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Article

Evidence for two types of cytotoxic necrotizing factor in human and animal clinical isolates of Escherichia coli

1 Apr 1990

Abstract excerpt

We have characterized the in vitro and in vivo toxic properties of cell sonic extracts from 22 animal and human clinical isolates of Escherichia coli that caused both necrosis in the rabbit skin and multinucleation in tissue cultures, two toxic properties previously reported as being specific for E. coli cytotoxic necrotizing factor (CNF). Two distinct toxic phenotypes were observed. Type 1, which was displayed...

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Identifiers

PMID: 2185259
DOI: 10.1128/jcm.28.4.694-699.1990

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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