Article
Diversity of the KIR gene cluster in an urban Brazilian population.
Immunogenetics - 1 Feb 2012
Augusto D G, Zehnder-Alves L, Pincerati M R, Martin M P, Carrington M, Petzl-Erler Maria Luiza
Abstract excerpt
The activity of natural killer cells depends on the balance between activating and inhibitory signals coming from their receptors. Among these are the killer cell immunoglobulin-like receptors (KIR) that recognize specific HLA class I allotypes. Here we characterized KIR genetic diversity and their HLA ligands in the population of Curitiba, Paraná State (n = 164), and compared it with other worldwide populations....
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