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Article

Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.

International journal of immunogenetics - 1 Apr 2010

Jobim M, Salim P H, Portela P, Wilson T J, Fraportti J, Baronio D, Gil B, Penna L S, Roesler R, Jobim L F, Schwartsmann G

Abstract excerpt

Killer immunoglobulin-like receptors (KIR) regulate the activity of natural killer and T cells through an interaction with specific human leucocyte antigen (HLA) class I molecules on target cells. Diversity in KIR gene content, KIR allelic and haplotype polymorphism has been observed between different ethnic groups. However, most population studies on KIR variability have focused on Europe and Asia, while...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20082646
DOI: 10.1111/j.1744-313X.2009.00894.x

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