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Article

Variants of HSPA1A in combination with plasma Hsp70 and anti-Hsp70 antibody levels associated with higher risk of acute coronary syndrome.

Cardiology - 1 Jan 2011

Zhang Xiaomin, Tanguay Robert M, He Mei'an, Deng Qifei, Miao Xiaoping, Zhou Li, Wu Tangchun

Abstract excerpt

OBJECTIVES: It was the aim of our study to investigate whether polymorphisms of HSP70 have an affect on antigen and antibody levels in acute coronary syndrome (ACS) patients and normal controls, and the possible joint effect of variants and antigen and antibody levels on the risk of ACS. METHODS: Three single nucleotide polymorphisms of HSPA1A and HSPA1L were evaluated in 520 ACS patients and 520 age- and...

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PMID: 21849784
DOI: 10.1159/000329917

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