Article
Effects of polymorphisms of heat shock protein 70 gene on ischemic stroke, and interaction with smoking in China.
Clinica chimica acta; international journal of clinical chemistry - 1 Sept 2007
Liu Jianping, Cheng Jinquan, Peng Ji, Han Shenghong, Yu Lei, Nie Shaofa
Abstract excerpt
BACKGROUND: Heat shock protein 70 (HSP70) plays a key role in up-regulating stress responses, and it may be involved in the pathogenesis of ischemic stroke (IS). However, whether HSP70 polymorphisms are a risk factor for IS is still controversial. METHODS: Three polymorphisms of HSP70 gene (+190G/C, +1267A/G, and +2437T/C) were analyzed by PCR-RFLP in Chinese patients with IS (n=116) and elderly subjects without...
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