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HSP70 and Primary Arterial Hypertension

1 Feb 2023

Abstract excerpt

Heat shock protein 70 (HSP70) production is a stress-generated cellular response with high interspecies homology. HSP70 has both chaperone and cytokine functions and may induce, depending on the context, tolerogenic anti-inflammatory reactivity or immunogenic and autoimmune reactivity. Intracellular (chaperoning transit of antigens to MHC in antigen-presenting cells) and extracellular HSP70-related effects are...

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PMID: 36830641
DOI: 10.3390/biom13020272

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