Article
Relationship between statin use and colon cancer recurrence and survival: results from CALGB 89803.
Journal of the National Cancer Institute - 19 Oct 2011
Ng Kimmie, Ogino Shuji, Meyerhardt Jeffrey A, Chan Jennifer A, Chan Andrew T, Niedzwiecki Donna, Hollis Donna, Saltz Leonard B, Mayer Robert J, Benson Al B, Schaefer Paul L, Whittom Renaud, Hantel Alexander, Goldberg Richard M, Bertagnolli Monica M, Venook Alan P, Fuchs Charles S
Abstract excerpt
BACKGROUND: Although preclinical and epidemiological data suggest that statins may have antineoplastic properties, the impact of statin use on patient survival after a curative resection of stage III colon cancer is unknown. METHODS: We conducted a prospective observational study of 842 patients with stage III colon cancer enrolled in a randomized adjuvant chemotherapy trial from April 1999 to May 2001 to...
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