Article
Relationship Between Metformin Use and Recurrence and Survival in Patients With Resected Stage III Colon Cancer Receiving Adjuvant Chemotherapy: Results From North Central Cancer Treatment Group N0147 (Alliance).
The oncologist - 1 Dec 2016
Singh Preet Paul, Shi Qian, Foster Nathan R, Grothey Axel, Nair Suresh G, Chan Emily, Shields Anthony F, Goldberg Richard M, Gill Sharlene, Kahlenberg Morton S, Sinicrope Frank A, Sargent Daniel J, Alberts Steven R
Abstract excerpt
BACKGROUND: Preclinical and epidemiological data suggest that metformin might have antineoplastic properties against colon cancer (CC). However, the effect of metformin use on patient survival in stage III CC after curative resection is unknown. The survival outcomes were comparable regardless of the duration of metformin use. PATIENTS AND METHODS: Before randomization to FOLFOX (folinic acid, 5-fluorouracil,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.