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Article

Extracting quantitative genetic interaction phenotypes from matrix combinatorial RNAi.

BMC bioinformatics - 17 Aug 2011

Axelsson Elin, Sandmann Thomas, Horn Thomas, Boutros Michael, Huber Wolfgang, Fischer Bernd

Abstract excerpt

BACKGROUND: Systematic measurement of genetic interactions by combinatorial RNAi (co-RNAi) is a powerful tool for mapping functional modules and discovering components. It also provides insights into the role of epistasis on the way from genotype to phenotype. The interpretation of co-RNAi data requires computational and statistical analysis in order to detect interactions reliably and sensitively. RESULTS: We...

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Identifiers

PMID: 21849035
DOI: 10.1186/1471-2105-12-342
PMCID: PMC3230910

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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