Article
Associations between gene polymorphisms in fatty acid metabolism pathway and preterm delivery in a US urban black population.
Human genetics - 1 Mar 2012
Liu Xin, Wang Guoying, Hong Xiumei, Tsai Hui-Ju, Liu Rong, Zhang Shanchun, Wang Hongjian, Pearson Colleen, Ortiz Katherin, Wang Deli, Hirsch Emmet, Zuckerman Barry, Wang Xiaobin
Abstract excerpt
There is increasing evidence suggesting that higher intakes of fish or n-3 polyunsaturated fatty acids supplements may decrease the risk of preterm delivery (PTD). We hypothesized that genetic variants of the enzymes critical to fatty acids biosynthesis and metabolism may be associated with PTD. We genotyped 231 potentially functional single nucleotide polymorphisms (SNPs) and tagSNPs in 9 genes (FADS1, FADS2,...
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