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Article

Maternal and fetal variation in genes of cholesterol metabolism is associated with preterm delivery.

Journal of perinatology : official journal of the California Perinatal Association - 1 Nov 2007

Steffen K M, Cooper M E, Shi M, Caprau D, Simhan H N, Dagle J M, Marazita M L, Murray J C

Abstract excerpt

OBJECTIVE: To examine the contribution of variants in fetal and maternal cholesterol metabolism genes in preterm delivery (PTD). STUDY DESIGN: A total of 40 single-nucleotide polymorphisms (SNPs) in 16 genes related to cholesterol metabolism were examined for 414 preterm infants (gestational ages 22 to 36 weeks; comprising 305 singletons and 109 twins) and at least 1 parent. Fetal effects were assessed using the...

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Source

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Identifiers

PMID: 17855807
DOI: 10.1038/sj.jp.7211806
PMCID: PMC2706423

Genes

ABCA1
HMGCR
APOA1
APOE
DHCR7

Provenance

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