Article
Differences in susceptibility among mouse strains to infection with Plasmodium berghei (ANKA clone) sporozoites and its relationship to protection by gamma-irradiated sporozoites.
The American journal of tropical medicine and hygiene - 1 Apr 1990
Jaffe R I, Lowell G H, Gordon D M
Abstract excerpt
Three inbred mouse strains, C57BL/6 (H-2b), A/J (H-2a), and BALB/c (H-2d), and 1 outbred strain, CD-1, demonstrated differences in susceptibility to iv challenge with the ANKA clone of Plasmodium berghei. Mice were challenged with 100, 1,000, or 10,000 sporozoites, then evaluated daily beginning...
Topics
- Animals
- Female
- Gamma Rays
- Genetic Predisposition to Disease
- Immunization
- Malaria
- Mice
- Mice, Inbred A
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Plasmodium berghei
- Species Specificity