Mutagenic DNA repair in Escherichia coli. XVIII. Involvement of DNA polymerase III alpha-subunit (DnaE protein) in mutagenesis after exposure to UV light.

doi:10.1093/mutage/5.1.35

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Article

Mutagenic DNA repair in Escherichia coli. XVIII. Involvement of DNA polymerase III alpha-subunit (DnaE protein) in mutagenesis after exposure to UV light.

Mutagenesis - 1 Jan 1990

Bridges B A, Bates H

Abstract excerpt

UV light was unable to induce rifampicin-resistant mutations at 43 degrees C in Escherichia coli ER11 dnaE486. Although DnaE486 gene product is inactive at 43 degrees C, these bacteria contain the pcbA1 mutation which allows DNA replication provided DNA polymerase I is functional. The experiments...

Topics

DNA Polymerase III
DNA Repair
DNA-Directed DNA Polymerase
Drug Resistance, Microbial
Escherichia coli
Mutation
Rifampin
Ultraviolet Rays

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