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Article

The evolution of heart gene delivery vectors

11 Aug 2011

Abstract excerpt

Gene therapy holds promise for treating numerous heart diseases. A key premise for the success of cardiac gene therapy is the development of powerful gene transfer vehicles that can achieve highly efficient and persistent gene transfer specifically in the heart. Other features of an ideal vector include negligible toxicity, minimal immunogenicity and easy manufacturing. Rapid progress in the fields of molecular...

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PMID: 21837689
DOI: 10.1002/jgm.1600

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