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Article

Adeno-Associated Virus Vectors as Therapeutic and Investigational Tools in the Cardiovascular System

22 May 2014

Abstract excerpt

The use of vectors based on the small parvovirus adeno-associated virus has gained significant momentum during the past decade. Their high efficiency of transduction of postmitotic tissues in vivo, such as heart, brain, and retina, renders these vectors extremely attractive for several gene therapy applications affecting these organs. Besides functional correction of different monogenic diseases, the possibility...

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PMID: 24855205
DOI: 10.1161/circresaha.114.302331

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