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Article

Development of Viral Vectors for Use in Cardiovascular Gene Therapy

27 Jan 2010

Abstract excerpt

Cardiovascular disease represents the most common cause of mortality in the developed world but, despite two decades of promising pre-clinical research and numerous clinical trials, cardiovascular gene transfer has so far failed to demonstrate convincing benefits in the clinical setting. In this review we discuss the various targets which may be suitable for cardiovascular gene therapy and the viral vectors which...

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PMID: 21994642
DOI: 10.3390/v2020334

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