Article
Metastatic melanoma with striking adenocarcinomatous differentiation illustrating phenotypic plasticity in melanoma.
The American journal of surgical pathology - 1 Sept 2011
Jalas John R, Vemula Swapna, Bezrookove Vladimir, Leboit Philip E, Simko Jeffry P, Bastian Boris C
Abstract excerpt
We report on the highly unusual case of a 75-year-old woman who developed a biphasic right axillary mass of apparent melanoma and adenocarcinoma 13 years after a diagnosis of primary melanoma on her right upper back. The differential diagnosis included a collision tumor and metastatic melanoma with adenocarcinomatous transdifferentiation. We utilized immunohistochemical staining, DNA sequencing, and comparative...
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