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Article

Progression of pancreatitis prior to diabetes onset in WBN/Kob-Lepr(fa) rats.

The Journal of veterinary medical science - 1 Jan 2012

Akimoto Toshio, Terada Misao, Shimizu Akira

Abstract excerpt

We established the WBN/Kob-Lepr(fa) rat as a new congenic strain for the fa allele of the leptin receptor gene (Lepr). Homozygous (fa/fa) WBN/Kob-Lepr(fa) rats provide a model of non-insulin-dependent diabetes, although its onset is secondary to pancreatitis. In the present study, we compared histopathological observations of pancreatitis in each genotype of this rat, to examine its suitability as a model of...

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Source

Identifiers

PMID: 21836382
DOI: 10.1292/jvms.11-0168

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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