Effect of partial pancreatectomy on beta-cell mass in the remnant pancreas of Wistar fatty rats.

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Article

Effect of partial pancreatectomy on beta-cell mass in the remnant pancreas of Wistar fatty rats.

The journal of medical investigation : JMI - 1 Aug 1998

Ogino T, Zhu M, Murakami T, Kuwajima M, Shima K

Abstract excerpt

Wistar fatty rat, which has been established by transferring the fa gene of Zucker fatty rat to the Wistar Kyoto rat, has many features in common with human NIDDM. It exhibits hyperglycemic obesity with hyperinsulinemia and insulin resistance. It is unclear, however, whether a defect in the beta-...

Topics

Animals
Blood Glucose
Cell Division
Diabetes Mellitus
Diabetes Mellitus, Type 2
Disease Models, Animal
Genotype
Hyperglycemia
Insulin
Insulin Resistance
Islets of Langerhans
Male
Niacinamide
Obesity
Pancreatectomy
Phenotype
Phlorhizin
Rats

Source

Open in PubMed

Identifiers

PMID: 9864970

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9864970-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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