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Transcriptome analysis of embryonic mammary cells reveals insights into mammary lineage establishment

11 Aug 2011

Abstract excerpt

INTRODUCTION: The mammary primordium forms during embryogenesis as a result of inductive interactions between its constitutive tissues, the mesenchyme and epithelium, and represents the earliest evidence of commitment to the mammary lineage. Previous studies of embryonic mouse mammary epithelium indicated that, by mid-gestation, these cells are determined to a mammary cell fate and that a stem cell population has...

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PMID: 21834968
DOI: 10.1186/bcr2928

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