Article
HLA alleles and amino-acid signatures of the peptide-binding pockets of HLA molecules in vitiligo.
The Journal of investigative dermatology - 1 Jan 2012
Singh Archana, Sharma Pankaj, Kar Hemanta K, Sharma Vinod K, Tembhre Manoj K, Gupta Somesh, Laddha Naresh C, Dwivedi Mitesh, Begum Rasheedunnisa, Gokhale Rajesh S, Rani Rajni
Abstract excerpt
Vitiligo is a depigmenting disorder of the skin that is characterized by the loss of functional melanocytes from the lesional sites. Although the exact etiology is not understood, autoimmunity is thought to be a crucial deterministic factor. A recurring theme of several autoimmune disorders is the aberrant presentation of self-antigens to the immune system, which triggers downstream perturbations. Here we examine...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
