Article
Identification of the Risk HLA-A Alleles and Autoantigen in Han Chinese Vitiligo Patients and the Association of CD8+T Cell Reactivity with Disease Characteristics.
Medical science monitor : international medical journal of experimental and clinical research - 16 Sept 2018
Yi Xiuli, Cui Tingting, Li Shuli, Yang Yuqi, Chen Jiaxi, Guo Sen, Jian Zhe, Li Chunying, Gao Tianwen, Liu Ling, Li Kai
Abstract excerpt
BACKGROUND Multiple studies have implicated a role for CD8+T cell-mediated immune response to autoantigens in vitiligo. However, the antigen-specific T lymphocyte reactivity against the peptide epitopes is diverse among different world populations. This study aimed to identify the risk HLA-A allele in vitiligo and study CD8+ T cell reactivity to 5 autoantigenic peptides in Han Chinese populations, and to analyze...
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