Article
Association of a common vitamin D-binding protein polymorphism with inflammatory bowel disease.
Pharmacogenetics and genomics - 1 Sept 2011
Eloranta Jyrki J, Wenger Christa, Mwinyi Jessica, Hiller Christian, Gubler Christoph, Vavricka Stephan R, Fried Michael, Kullak-Ublick Gerd A
Abstract excerpt
OBJECTIVE: Inflammatory bowel diseases (IBDs), Crohn's disease, and ulcerative colitis (UC), are multifactorial disorders, characterized by chronic inflammation of the intestine. A number of genetic components have been proposed to contribute to IBD pathogenesis. In this case-control study, we investigated the association between two common vitamin D-binding protein (DBP) genetic variants and IBD susceptibility....
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