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Article

Vitamin D receptor gene polymorphism: association with Crohn's disease susceptibility.

Gut - 1 Aug 2000

Simmons J D, Mullighan C, Welsh K I, Jewell D P

Abstract excerpt

BACKGROUND: The vitamin D receptor (VDR) gene represents a strong positional candidate susceptibility gene for inflammatory bowel disease (IBD). The VDR gene maps to a region on chromosome 12 that has been shown to be linked to IBD by genome screening techniques. It is the cellular receptor for 1,25(OH)(2) vitamin D(3) (calcitriol) which has a wide range of different regulatory effects on the immune system. IBD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colitis, Ulcerative

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Share to Polymorphism, Genetic

Share to Receptors, Calcitriol

Source

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Identifiers

PMID: 10896912
DOI: 10.1136/gut.47.2.211
PMCID: PMC1728007

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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