Article
Associations between polymorphic variants of the tryptophan hydroxylase 2 gene and obsessive-compulsive disorder.
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) - 1 Jun 2011
Rocha Felipe Filardi da, Alvarenga Nathália Bueno, Lage Naira Vassalo, Romano-Silva Marco Aurélio, Marco Luiz Armando de, Corrêa Humberto
Abstract excerpt
OBJECTIVE: A substantial body of evidence suggests that obsessive-compulsive disorder has a genetic component, and substantial candidate genes for the disorder have been investigated through association analyses. A particular emphasis has been placed on genes related to the serotonergic system, which is likely to play an important role in the pathogenesis of obsessive-compulsive disorder. The gene for tryptophan...
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