Functional contribution of cysteine residues to the human immunodeficiency virus type 1 envelope.

doi:10.1128/JVI.64.5.2250-2259.1990

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Article

Functional contribution of cysteine residues to the human immunodeficiency virus type 1 envelope.

Journal of virology - 1 May 1990

Tschachler E, Buchow H, Gallo R C, Reitz M S

Abstract excerpt

Although the envelope gene of human immunodeficiency virus type 1 shows considerable strain variability, cysteine residues of the envelope protein are strongly conserved, suggesting that they are important to the envelope structure. We constructed and analyzed mutants of a biologically active molecular clone of human immunodeficiency virus type 1 in which different cysteines were replaced by other amino acids in...

Topics

Amino Acid Sequence
Animals
Antigens, CD
Antigens, Surface
Base Sequence
CD4 Antigens
Cell Line
Cysteine
Fluorescent Antibody Technique
Genes, Viral
Giant Cells
HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HeLa Cells

Humans

Molecular Sequence Data

Mutation

Oligonucleotide Probes

Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 2182910
DOI: 10.1128/JVI.64.5.2250-2259.1990
PMCID: PMC249386

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2182910-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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