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Article

A test of Hardy-Weinberg equilibrium in structured populations.

Genetic epidemiology - 1 Nov 2011

Sha Qiuying, Zhang Shuanglin

Abstract excerpt

Testing for Hardy-Weinberg equilibrium (HWE) is used routinely as an important initial step for genotype data quality checking. Departure from HWE can be caused by many factors, such as genotyping errors, population stratification, and disease association, if we use affected individuals only. In a structured population, even if a marker is in HWE in each subpopulation, data may show departure from HWE if allele...

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PMID: 21818775
DOI: 10.1002/gepi.20617

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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