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Article

Peripheral blood monocyte-expressed ANXA2 gene is involved in pathogenesis of osteoporosis in humans.

Molecular & cellular proteomics : MCP - 1 Nov 2011

Deng Fei-Yan, Lei Shu-Feng, Zhang Yan, Zhang Yu-Ling, Zheng Yan-Peng, Zhang Li-Shu, Pan Rong, Wang Lili, Tian Qing, Shen Hui, Zhao Ming, Lundberg Yunxia Wang, Liu Yao-Zhong, Papasian Christopher J, Deng Hong-Wen

Abstract excerpt

Low bone mineral density (BMD) is a risk factor of osteoporosis and has strong genetic determination. Genes influencing BMD and fundamental mechanisms leading to osteoporosis have yet to be fully determined. Peripheral blood monocytes (PBM) are potential osteoclast precursors, which could access to bone resorption surfaces and differentiate into osteoclasts to resorb bone. Herein, we attempted to identify...

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Identifiers

PMID: 21817168
DOI: 10.1074/mcp.M111.011700
PMCID: PMC3226411

Genes

ANXA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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