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Article

Gene expression profiling in monocytes and SNP association suggest the importance of the STAT1 gene for osteoporosis in both Chinese and Caucasians.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Feb 2010

Chen Xiang-Ding, Xiao Peng, Lei Shu-Feng, Liu Yao-Zhong, Guo Yan-Fang, Deng Fei-Yan, Tan Li-Jun, Zhu Xue-Zhen, Chen Fu-Rong, Recker Robert R, Deng Hong-Wen

Abstract excerpt

Osteoporosis is characterized mainly by low bone mineral density (BMD). Many cytokines and chemokines have been related with bone metabolism. Monocytes in the immune system are important sources of cytokines and chemokines for bone metabolism. However, no study has investigated in vivo expression of a large number of various factors simultaneously in human monocytes underlying osteoporosis. This study explored...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19594299
DOI: 10.1359/jbmr.090724
PMCID: PMC3153389

Genes

STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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