Article
Network based subcellular proteomics in monocyte membrane revealed novel candidate genes involved in osteoporosis.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Oct 2017
Zeng Y, Zhang L, Zhu W, He H, Sheng H, Tian Q, Deng F-Y, Zhang L-S, Hu H-G, Deng H-W
Abstract excerpt
In this study, label-free-based quantitative subcellular proteomics integrated with network analysis highlighted several candidate genes including P4HB, ITGB1, CD36, and ACTN1 that may be involved in osteoporosis. All of them are predicted as significant membrane proteins with high confidence and enriched in bone-related biological process. The results were further verified in transcriptomic and genomic levels....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.