A Single-Nucleotide Polymorphism of miR-196a2T>C rs11614913 Is Associated with Hepatocellular Carcinoma in the Chinese Population.

doi:10.1089/gtmb.2015.0271

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Article

A Single-Nucleotide Polymorphism of miR-196a2T>C rs11614913 Is Associated with Hepatocellular Carcinoma in the Chinese Population.

Genetic testing and molecular biomarkers - 1 Apr 2016

Li Juan, Cheng Guilian, Wang Shaofeng

Abstract excerpt

OBJECTIVE: We investigated the miR-196a2T>C rs11614913 variant in the initiation and progression of hepatocellular carcinoma (HCC). METHODS: A case-control research model was conducted and the genotypes of 109 HCC patients and 105 healthy controls were identified by direct sequencing. The correlation between the rs11614913 genotypes and the susceptibility to HCC was evaluated using an unconditional logistic...

Topics

Adult
Asian People
Carcinoma, Hepatocellular
Case-Control Studies
Female
Genetic Predisposition to Disease
Genotype
Humans
Liver Neoplasms
Male
MicroRNAs
Middle Aged
Polymorphism, Single Nucleotide
Prognosis
Risk Factors

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Open in PubMed

Identifiers

PMID: 26866381
DOI: 10.1089/gtmb.2015.0271

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