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Article

Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 3 Aug 2011

Mildner Alexander, Schlevogt Bernhard, Kierdorf Katrin, Böttcher Chotima, Erny Daniel, Kummer Markus P, Quinn Michael, Brück Wolfgang, Bechmann Ingo, Heneka Michael T, Priller Josef, Prinz Marco

Abstract excerpt

Mononuclear phagocytes are important modulators of Alzheimer's disease (AD), but the specific functions of resident microglia, bone marrow-derived mononuclear cells, and perivascular macrophages have not been resolved. To elucidate the spatiotemporal roles of mononuclear phagocytes during disease, we targeted myeloid cell subsets from different compartments and examined disease pathogenesis in three different...

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Identifiers

PMID: 21813677
DOI: 10.1523/JNEUROSCI.6209-10.2011
PMCID: PMC6623351

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CCR2
APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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