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Article

AMPK γ2 subunit gene PRKAG2 polymorphism associated with cognitive impairment as well as diabetes in old age.

Psychoneuroendocrinology - 1 Mar 2012

Kim Eosu, Lee Sung Hee, Lee Kang Soo, Cheong Hae-Kwan, Namkoong Kee, Hong Chang Hyung, Oh Byoung Hoon

Abstract excerpt

Metabolic and cognitive disorders are closely related. However, the molecular mechanism underlying this association is still elusive. Given the importance of energy metabolism in neuronal cells, AMP-activated protein kinase (AMPK), a master switch of energy metabolism, could be an independent factor affecting cognitive as well as metabolic functions. Therefore, we examined the relationship between the AMPK γ2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21813245
DOI: 10.1016/j.psyneuen.2011.07.005

Genes

PRKAG2
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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