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Article

Association of a citrate synthase missense mutation with age-related hearing loss in A/J mice.

Neurobiology of aging - 1 Aug 2012

Johnson Kenneth R, Gagnon Leona H, Longo-Guess Chantal, Kane Kelly L

Abstract excerpt

We previously mapped a locus (ahl4) on distal Chromosome 10 that contributes to the age-related hearing loss of A/J strain mice. Here, we report on a refined genetic map position for ahl4 and its association with a mutation in the citrate synthase gene (Cs). We mapped ahl4 to the distal-most 7 megabases (Mb) of chromosome 10 by analysis of a new linkage backcross and then further narrowed the interval to 5.5 Mb...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 21803452
DOI: 10.1016/j.neurobiolaging.2011.05.009
PMCID: PMC3206989

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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