Article
JAK2V617F mutation in chronic myeloid leukemia predicts early disease progression.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP - 1 Aug 2011
Pahore Zaen-Al-Abideen, Shamsi Tahir S, Taj Mehwesh, Farzana Tasneem, Ansari Saqib H, Nadeem Muhammad, Ahmad Masood, Naz Arshi
Abstract excerpt
OBJECTIVE: To determine the association of JAK2V617F mutation along with BCR-ABL translocation or Philadelphia chromosome in chronic myeloid leukemia with early disease progression to advanced stages (accelerated phase or blast crisis) and poor outcome. STUDY DESIGN: Case series. PLACE AND DURATION OF STUDY: National Institute of Blood Diseases and Bone Marrow Transplantation, Karachi, from February 2008 to...
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