Article
Association of a mast cell chymase gene variant with HDL cholesterol, but not with blood pressure in the Ohasama study.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Mar 2002
Fukuda Masayuki, Ohkubo Takayoshi, Katsuya Tomohiro, Hozawa Atsushi, Asai Takashi, Matsubara Mitsunobu, Kitaoka Hirofumi, Tsuji Ichiro, Araki Tsutomu, Satoh Hiroshi, Higaki Jitsuo, Hisamichi Shigeru, Imai Yutaka, Ogihara Toshio
Abstract excerpt
Two enzymes, chymase and angiotensin converting enzyme (ACE), are involved in the production of angiotensin II. Our previous study revealed the male-specific effect of the ACE DD genotype on the risk for hypertension, but the genetic role of chymase remains unclear. In the present study, we report the results of an association study involving 1,046 subjects recruited from a general population in Ohasama, a rural...
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