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Article

Association of the single-nucleotide polymorphism in the MFG-E8 gene with coronary heart disease in Chinese Han population.

BMC cardiovascular disorders - 24 May 2025

Wang Di, Liu WenHui, Wang LiLi, Zhang Ning, Huang XiaoFeng, Chen HuoYing

Abstract excerpt

Coronary atherosclerosis narrows or occludes blood vessels, resulting in myocardial ischemia and hypoxia, which ultimately leads to coronary heart disease (CHD). The pathogenesis of CHD remains insufficiently elucidated. A widely accepted hypothesis is that various stimuli induce arterial intima injury, and atherosclerosis (AS)formation reflects the inflammatory-fibroproliferative response of the intima to such...

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PMID: 40413414
DOI: 10.1186/s12872-025-04860-z
PMCID: PMC12102855

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