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Integrated analysis of DNA methylation profile of HLA-G gene and imaging in coronary heart disease: Pilot study

13 Aug 2020

Abstract excerpt

AIMS: Immune endothelial inflammation, underlying coronary heart disease (CHD) related phenotypes, could provide new insight into the pathobiology of the disease. We investigated DNA methylation level of the unique CpG island of HLA-G gene in CHD patients and evaluated the correlation with cardiac computed tomography angiography (CCTA) features. METHODS: Thirty-two patients that underwent CCTA for suspected CHD...

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PMID: 32790754
DOI: 10.1371/journal.pone.0236951

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