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<i>Trichinella spiralis</i> antigens prime mixed Th1/Th2 response but do not induce <i>de novo</i> generation of Foxp3<sup>+</sup> T cells <i>in vitro</i>

27 Jul 2011

Abstract excerpt

Many parasitic helminth infections induce Th2-type immune responses and engage the regulatory network. In this study, we specifically investigated the influence of antigens derived from different life stages of the helminth Trichinella spiralis on the polarization of naive CD4(+) T cells by dendritic cells. Results obtained from C57BL/6 mice showed that T. spiralis derived antigens have the capacity to induce...

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PMID: 21793858
DOI: 10.1111/j.1365-3024.2011.01322.x

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