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NLRP3 played a role in Trichinella spiralis-triggered Th2 and regulatory T cells response

27 Aug 2020

Abstract excerpt

Abstract Trichinella spiralis maintains chronic infections within its host. Muscle larvae excretory-secretory products (MLES) typically induce parasite-specific immune responses such as the Th2 response and regulatory T cells (Tregs) by modulating dendritic cell (DC) phenotype via the recognition of pattern recognition receptors (PRRs), such as Nod-like receptors (NLRs). We aimed to investigate the role of NLRP3...

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PMID: 32854770
DOI: 10.1186/s13567-020-00829-2

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