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Article

The cancer stem cell niche—there goes the neighborhood?

26 Jul 2011

Abstract excerpt

The niche is the environment in which stem cells reside and is responsible for the maintenance of unique stem cell properties such as self-renewal and an undifferentiated state. The heterogeneous populations which constitute a niche include both stem cells and surrounding differentiated cells. This network of heterogeneity is responsible for the control of the necessary pathways that function in determining stem...

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PMID: 21792897
DOI: 10.1002/ijc.26312

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