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Article

The Role of the Microenvironment and Immune System in Regulating Stem Cell Fate in Cancer

26 Jan 2021

Abstract excerpt

Despite gains in knowledge of the intrinsic signals governing cancer progression, effective clinical management of cancer remains a challenge. Drug resistance and relapse, pose the greatest barriers to cancer care, and are often driven by the co-option of stem cell programs by subpopulations of aggressive cancer cells. Here, we focus on the role of the microenvironment in the acquisition and/or maintenance of...

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Identifiers

PMID: 33509688
DOI: 10.1016/j.trecan.2020.12.014

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