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Article

High CD33 expression levels in acute myeloid leukemia cells carrying the nucleophosmin (NPM1) mutation.

Haematologica - 1 Oct 2011

De Propris Maria Stefania, Raponi Sara, Diverio Daniela, Milani Maria Laura, Meloni Giovanna, Falini Brunangelo, Foà Robin, Guarini Anna

Abstract excerpt

The CD33 antigen is expressed on the blast cells of most cases of acute myeloid leukemia and represents a suitable tumor-associated target antigen for antibody-based therapies. The aim of this study was to investigate the relationship between the CD33 levels quantified by mean fluorescence intensity and antibody binding capacity, and the presence/absence of NPM1 and FLT3 gene mutations in 99 newly diagnosed acute...

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Source

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Identifiers

PMID: 21791474
DOI: 10.3324/haematol.2011.043786
PMCID: PMC3186318

Genes

NPM1
FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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