Article
Expression of myeloid differentiation antigens in acute nonlymphocytic leukemia: increased concentration of CD33 antigen predicts poor outcome--a report from the Childrens Cancer Study Group.
Medical and pediatric oncology - 1 Jan 1992
Dinndorf P A, Buckley J D, Nesbit M E, Lampkin B C, Piomelli S, Feig S A, Kersey J H, Hammond G D, Bernstein I D
Abstract excerpt
Ninety-eight cryopreserved specimens of acute nonlymphocytic leukemia (ANLL) cells obtained at initial diagnosis of children enrolled on the Childrens Cancer Study Group 251 protocol (CCG 251) were examined by indirect immunofluorescence using four monoclonal antibodies to myeloid differentiation antigens. The relationship between the level of differentiation of ANLL cells as determined by their antigen phenotype...
Topics
- Antibodies, Monoclonal
- Antigens, CD
- Antigens, Differentiation, Myelomonocytic
- Child
- Fluorescent Antibody Technique
- Follow-Up Studies
- Gene Expression
- Humans
- Leukemia, Myeloid, Acute