Article
High-dose cytarabine plus gemtuzumab ozogamicin as consolidation therapy in patients with favorable- or intermediate-risk acute myeloid leukemia.
International journal of hematology - 1 Sept 2024
Oya Shuki, Ozawa Hidetoshi, Morishige Satoshi, Maehiro Yoshimi, Umeda Masahiro, Takaki Yusuke, Fukuyama Toshinobu, Yamasaki Yoshitaka, Nakamura Takayuki, Yamaguchi Maki, Aoyama Kazutoshi, Mouri Fumihiko, Nagafuji Koji
Abstract excerpt
Previous prospective randomized trials have investigated the efficacy of gemtuzumab ozogamicin in the frontline treatment of acute myeloid leukemia (AML). We evaluated the efficacy of high-dose cytarabine with GO as consolidation therapy in 20 patients with favorable- or intermediate-risk AML in first complete remission. They included six patients with wild-type nucleophosmin (NPM1) core binding factor (CBF), ten...
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