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Article

CCND1 1722 polymorphism and potential relevance to upper tract urothelial cancer.

Anticancer research - 1 Mar 2011

Lin Hui-Hui, Ke Hung-Lung, Hsiao Kuang-Hung, Tsai Chia-Wen, Wu Wen-Jeng, Bau Da-Tian, Chang Lin-Li

Abstract excerpt

BACKGROUND: The cell cycle regulator cyclin D1 (CCND1) is thought to play a major role in the transition of the cell cycle from G1 to S-phase. It is known that cancer cells have unbalanced cell cycle regulation. However, the genetic role of CCND1 in urothelial cancer (UC) is not known. This study was conducted to explore the association between the CCND1 C1722G polymorphism and the susceptibility and progression...

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Source

Identifiers

PMID: 21498736

Genes

CCND1

Variants

Provenance

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