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Article

Mitochondrial transporter ATP binding cassette mitochondrial erythroid is a novel gene required for cardiac recovery after ischemia/reperfusion.

Circulation - 16 Aug 2011

Liesa Marc, Luptak Ivan, Qin Fuzhong, Hyde Brigham B, Sahin Ergun, Siwik Deborah A, Zhu Zhengkun, Pimentel David R, Xu X Julia, Ruderman Neil B, Huffman Karl D, Doctrow Susan R, Richey Lauren, Colucci Wilson S, Shirihai Orian S

Abstract excerpt

BACKGROUND: Oxidative stress and mitochondrial dysfunction are central mediators of cardiac dysfunction after ischemia/reperfusion. ATP binding cassette mitochondrial erythroid (ABC-me; ABCB10; mABC2) is a mitochondrial transporter highly induced during erythroid differentiation and predominantly expressed in bone marrow, liver, and heart. Until now, ABC-me function in heart was unknown. Several lines of evidence...

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Identifiers

PMID: 21788586
DOI: 10.1161/CIRCULATIONAHA.110.003418
PMCID: PMC4491919

Genes

ABCB10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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