Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cardiomyocyte-specific deletion of the mitochondrial transporter Abcb10 causes cardiac dysfunction via lysosomal-mediated ferroptosis

24 Apr 2024

Abstract excerpt

Heart function is highly dependent on mitochondria, which not only produce energy but also regulate many cellular functions. Therefore, mitochondria are important therapeutic targets in heart failure. Abcb10 is a member of the ABC transporter superfamily located in the inner mitochondrial membrane and plays an important role in haemoglobin synthesis, biliverdin transport, antioxidant stress, and stabilization of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circular RNAs in diseases
Share to Ferroptosis and cancer prognosis
Share to Trace Elements in Health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38655715
DOI: 10.1042/bsr20231992

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cardiomyocyte-specific deletion of the mitochondrial transporter Abcb10 causes cardiac dysfunction via lysosomal-mediated ferroptosisPMID 38655715Read ↗

Ferroptosis and its role in cardiomyopathySemantic proximity Read ↗

Early mitophagy defects and impaired mitochondrial energy metabolism drive target organ damage progression: lessons from the Fabry heartSemantic proximity Read ↗

An Alternative Mechanism of Subcellular Iron Uptake Deficiency in Cardiomyocytes.Semantic proximity Read ↗

The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron–sulfur cluster biogenesisSemantic proximity Read ↗

Mitochondria and Doxorubicin-Induced Cardiomyopathy: A Complex InterplaySemantic proximity Read ↗

Ferroptosis Is a Potential Novel Diagnostic and Therapeutic Target for Patients With CardiomyopathySemantic proximity Read ↗

Genetic analysis of potential biomarkers and therapeutic targets in ferroptosis from coronary artery diseaseSemantic proximity Read ↗

Epigenetic regulation and post-translational modifications of ferroptosis-related factors in cardiovascular diseasesSemantic proximity Read ↗

From bench to bedside: targeting ferroptosis and mitochondrial damage in the treatment of diabetic cardiomyopathySemantic proximity Read ↗

SLC40A1 in iron metabolism, ferroptosis, and disease: A reviewSemantic proximity Read ↗

BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytesSemantic proximity Read ↗

Down-regulation of HSPB1 and MGST1 promote ferroptosis and impact immune infiltration in diabetic cardiomyopathySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.